hrp0086rfc12.7 | Neuroendocrinology | ESPE2016

Prevalence of Organic Lesions in Males with Central Precocious Puberty

Pedicelli Stefania , De Matteis Sara , Scire Giuseppe , Cappa Marco , Cianfarani Stefano

Background: Organic lesions in males with central precocious puberty (CPP) have been reported in 40% of cases. This high prevalence decreases (20–29%) when patients with previously diagnosed alterations of central nervous system (CNS) are excluded. Reported predictors of organic lesions are age at puberty onset, bone age, BMI, LH peak response and testosterone levels.Objective and hypotheses: To determine the prevalence and type of intracranial lesi...